Male Infertility
Azoospermia — Non-obstructive
No sperm in ejaculate due to impaired sperm production. Sperm may still be retrieved from the testis via mTESE in ~50–60% of cases.
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Overview
Overview
No sperm in ejaculate due to impaired sperm production. Sperm may still be retrieved from the testis via mTESE in ~50–60% of cases.
Symptoms
No sperm on semen analysis
Small testes
Elevated FSH
Possible Klinefelter features
Causes
1
Klinefelter syndrome (47,XXY)2
Y-chromosome microdeletions3
Cryptorchidism4
Chemotherapy/radiation5
IdiopathicHow It's Diagnosed
Semen analysis (repeated)
FSH, LH, testosterone (elevated FSH, low testosterone)
Karyotype
Y-chromosome microdeletion panel
Testicular biopsy / mTESE
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