General
Balanced Chromosomal Translocation
One partner carries a balanced chromosomal rearrangement with no personal health impact, but gametes can carry unbalanced chromosomes causing recurrent miscarriage.
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Overview
Overview
One partner carries a balanced chromosomal rearrangement with no personal health impact, but gametes can carry unbalanced chromosomes causing recurrent miscarriage.
Symptoms
Recurrent miscarriage
Chromosomally abnormal offspring
Infertility
Identified on karyotype
Causes
1
De novo balanced translocation2
Inherited from carrier parentHow It's Diagnosed
Peripheral blood karyotype (both partners)
Products of conception karyotype if available
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