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Iswarya Fertility Centre & Women's Hospital
Iswarya
Fertility Centre
General

Balanced Chromosomal Translocation

One partner carries a balanced chromosomal rearrangement with no personal health impact, but gametes can carry unbalanced chromosomes causing recurrent miscarriage.

Overview

Overview

One partner carries a balanced chromosomal rearrangement with no personal health impact, but gametes can carry unbalanced chromosomes causing recurrent miscarriage.

Symptoms

Recurrent miscarriage
Chromosomally abnormal offspring
Infertility
Identified on karyotype

Causes

1
De novo balanced translocation
2
Inherited from carrier parent

How It's Diagnosed

Peripheral blood karyotype (both partners)
Products of conception karyotype if available

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Balanced Chromosomal Translocation — Causes, Symptoms & Treatment | Iswarya Fertility | Iswarya Fertility