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Iswarya Fertility Centre & Women's Hospital
Iswarya
Fertility Centre
General

Chromosomal Aneuploidy in Embryos

Most miscarriages are caused by chromosomally abnormal embryos. Risk increases steeply with maternal age — at 40, >60% of embryos are aneuploid.

Overview

Overview

Most miscarriages are caused by chromosomally abnormal embryos. Risk increases steeply with maternal age — at 40, >60% of embryos are aneuploid.

Symptoms

Recurrent miscarriage
Failed IVF cycles
Advanced maternal age (>35)

Causes

1
Age-related meiotic errors
2
Sperm chromosomal abnormalities
3
Parental chromosomal rearrangement

How It's Diagnosed

PGT-A on IVF embryos
Products of conception karyotype
Parental karyotype

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