General
Chromosomal Aneuploidy in Embryos
Most miscarriages are caused by chromosomally abnormal embryos. Risk increases steeply with maternal age — at 40, >60% of embryos are aneuploid.
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Overview
Overview
Most miscarriages are caused by chromosomally abnormal embryos. Risk increases steeply with maternal age — at 40, >60% of embryos are aneuploid.
Symptoms
Recurrent miscarriage
Failed IVF cycles
Advanced maternal age (>35)
Causes
1
Age-related meiotic errors2
Sperm chromosomal abnormalities3
Parental chromosomal rearrangementHow It's Diagnosed
PGT-A on IVF embryos
Products of conception karyotype
Parental karyotype
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