Female Infertility
Cushing Syndrome
Prolonged exposure to high cortisol levels disrupts the HPG axis, suppressing ovulation and causing metabolic and reproductive dysfunction.
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Overview
Overview
Prolonged exposure to high cortisol levels disrupts the HPG axis, suppressing ovulation and causing metabolic and reproductive dysfunction.
Symptoms
Central weight gain
Moon face
Purple striae
Irregular or absent periods
Infertility
Hypertension
Causes
1
Pituitary adenoma2
Adrenal adenoma3
Ectopic ACTH secretion4
Exogenous steroid useHow It's Diagnosed
24-hour urinary cortisol
Overnight dexamethasone suppression test
Morning cortisol
MRI pituitary/adrenal
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