Cushing Syndrome

Prolonged exposure to high cortisol levels disrupts the HPG axis, suppressing ovulation and causing metabolic and reproductive dysfunction.

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Prolonged exposure to high cortisol levels disrupts the HPG axis, suppressing ovulation and causing metabolic and reproductive dysfunction.

Central weight gain

Moon face

Purple striae

Irregular or absent periods

Infertility

Hypertension

Pituitary adenoma

Adrenal adenoma

Ectopic ACTH secretion

Exogenous steroid use

24-hour urinary cortisol

Overnight dexamethasone suppression test

Morning cortisol

MRI pituitary/adrenal

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