Female Infertility
Luteinised Unruptured Follicle Syndrome
The dominant follicle undergoes luteinisation but does not rupture to release the egg despite normal LH surge and progesterone rise.
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Overview
Overview
The dominant follicle undergoes luteinisation but does not rupture to release the egg despite normal LH surge and progesterone rise.
Symptoms
Regular cycles with normal progesterone yet no conception
No egg released on follicle tracking scans
Unexplained infertility
Causes
1
Peritoneal endometriosis2
NSAIDs use around ovulation3
Elevated LH at mid-cycle4
Pelvic adhesionsHow It's Diagnosed
Serial follicle tracking ultrasound
Progesterone on Day 21
Diagnostic laparoscopy if recurrent
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