Female Infertility
Premature Ovarian Failure Risk Assessment
Women with family history of early menopause, FMR1 premutation, or autoimmune conditions should have proactive ovarian reserve testing and fertility counselling.
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Overview
Overview
Women with family history of early menopause, FMR1 premutation, or autoimmune conditions should have proactive ovarian reserve testing and fertility counselling.
Symptoms
Family history of menopause before 45
Symptoms suggesting declining oestrogen in 30s
Low AMH or elevated FSH
Causes
1
Genetic (FMR1 premutation, BRCA2)2
Autoimmune ovarian insufficiency3
Family history without identifiable mutationHow It's Diagnosed
AMH and AFC (urgently)
FMR1 testing
Karyotype
Autoimmune ovarian antibodies
Day 3 FSH
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