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Patient guide

Male Fertility: Improving Sperm Quality

Practical steps men can take to improve sperm count, motility, and DNA quality โ€” covering lifestyle changes, supplements, and medical treatments.

Why Sperm Health Matters

Male factor contributes to infertility in approximately 50% of cases. The good news: sperm renew every 72โ€“74 days. With the right changes, meaningful improvement is possible within 3 months.

Lifestyle Changes with the Strongest Evidence

  • Stop Smoking: Damages sperm DNA, reduces count and motility
  • Limit Alcohol: Reduces testosterone; aim for <3โ€“4 units/week during fertility period
  • Maintain Healthy Weight: BMI 20โ€“25 is optimal for sperm parameters
  • Avoid Heat: No hot baths or saunas; avoid laptops directly on lap; loose-fitting cotton underwear
  • Exercise Moderately: 30 min, 5 days/week improves sperm; avoid excessive endurance exercise or steroid use

Supplements with Evidence

  • CoQ10: 200โ€“400 mg/day โ€” improves mitochondrial energy; motility
  • Vitamin C: 1000 mg/day โ€” antioxidant; reduces DNA fragmentation
  • Zinc: 25โ€“50 mg/day โ€” sperm production, testosterone
  • Selenium: 100โ€“200 mcg/day โ€” motility, antioxidant
  • Omega-3: 1โ€“2 g EPA+DHA โ€” DHA concentrated in sperm tail membrane

Medical Treatments

  • Varicocele repair: microsurgical varicocelectomy improves parameters in ~70% of men
  • Antibiotics for genital tract infection
  • Hormonal therapy for hypogonadism
  • Surgical sperm retrieval for azoospermia (TESA, PESA, mTESE)
  • ICSI bypasses most sperm abnormalities