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Iswarya Fertility Centre & Women's Hospital

Female Infertility Treatment

PCOS Treatment
Polycystic Ovary Syndrome

PCOS is the most common hormonal disorder in women of reproductive age and the leading cause of anovulatory infertility. With the right treatment, most women with PCOS can successfully achieve pregnancy.

70-80%
Conceive with treatment
1 in 5
Women has PCOS
39+
Years experience
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What is PCOS?

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder affecting approximately 1 in 5 women of reproductive age. It is characterised by a combination of irregular menstrual cycles, elevated male hormones (androgens), and polycystic ovaries visible on ultrasound.

PCOS is the most common cause of anovulatory infertility — infertility caused by the failure to ovulate regularly. The good news is that it is also one of the most treatable causes of infertility.

The exact cause of PCOS is not fully understood but involves insulin resistance, genetic factors, and hormonal imbalances. Treatment is tailored to each patient's symptoms, fertility goals, and overall health.

Diagnostic Criteria (Rotterdam)

PCOS is diagnosed when 2 out of 3 of the following are present:

  • 1Irregular or absent ovulation (anovulation)
  • 2Elevated male hormones (androgens) — clinical or biochemical signs
  • 3Polycystic ovaries on ultrasound (≥12 follicles in an ovary, or ovarian volume >10 ml)

Signs & Symptoms of PCOS

📅

Irregular Periods

Infrequent, irregular, or prolonged menstrual cycles — a hallmark of PCOS

🔬

Polycystic Ovaries

Multiple small follicles (cysts) visible on ovarian ultrasound scan

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Elevated Androgens

High testosterone causing acne, excess body/facial hair (hirsutism), and hair thinning

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Weight Gain

Insulin resistance leading to weight gain, especially around the abdomen

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Anovulation

Failure to release an egg (ovulate) regularly — the main cause of PCOS-related infertility

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Absent Periods

Some women with PCOS may have very few periods or none at all (amenorrhoea)

Treatment Options for PCOS

A step-by-step approach from least to most interventional

Lifestyle Modification

First Line

In overweight women, a 5-10% reduction in body weight through diet and exercise can restore ovulation naturally. This is the first-line treatment for PCOS.

Ovulation Induction

Most Common

Oral medications (letrozole or clomiphene) or low-dose FSH injections stimulate the ovaries to produce and release eggs. Monitoring via ultrasound ensures optimal response.

IUI (Intrauterine Insemination)

Step 2

Combined with ovulation induction, IUI places prepared sperm directly into the uterus during the fertile window — increasing the chance of fertilisation.

IVF (In Vitro Fertilization)

Advanced

Recommended when ovulation induction and IUI fail, or when there are additional fertility factors. Modified stimulation protocols prevent ovarian hyperstimulation (OHSS) in PCOS.

Insulin-Sensitising Agents

Adjunct

Metformin and inositol improve insulin sensitivity, regulate periods, and enhance the response to ovulation induction medications.

Laparoscopic Ovarian Drilling

Surgical

A minimally invasive surgical option for PCOS patients who don't respond to medications. Small holes are made in the ovary to reduce androgen production and restore ovulation.

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Frequently Asked Questions

PCOS & fertility — answers from our specialists

Yes. Most women with PCOS can achieve pregnancy with the right treatment. PCOS is one of the most common causes of infertility, but it is also one of the most treatable. Success rates with ovulation induction, IUI, and IVF are excellent. Many women with PCOS have successfully conceived at Iswarya Fertility.

Treatment depends on individual factors. Lifestyle modification is the first step for overweight women. Letrozole is the most effective ovulation induction medication for PCOS (better than clomiphene). If these fail, IUI with ovulation induction is tried. IVF is recommended for women with additional fertility factors or after multiple failed IUI cycles.

PCOS cannot be cured, but its symptoms can be effectively managed. With appropriate treatment — lifestyle changes, medications, and fertility treatments — most women with PCOS can achieve pregnancy and manage their long-term health effectively.

Yes, with proper protocols. Women with PCOS are at higher risk for ovarian hyperstimulation syndrome (OHSS) during IVF. At Iswarya Fertility, we use PCOS-specific stimulation protocols — including GnRH antagonist protocols, lower FSH doses, and "freeze-all" embryo strategies — to minimise OHSS risk while maximising success rates.

Ovulation induction cycles typically take 2-4 weeks per cycle. Most doctors recommend 3-6 cycles of ovulation induction before advancing to IUI, and 3-4 IUI cycles before proceeding to IVF. The total treatment timeline varies by individual, but many women conceive within 6-12 months of starting treatment.

Yes, significantly. A low glycemic index (GI) diet reduces insulin resistance, which improves hormonal balance and ovulation regularity. Achieving a healthy body weight can restore natural ovulation in many PCOS women. Regular exercise also improves insulin sensitivity and supports fertility.

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