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Iswarya Fertility Centre & Women's Hospital

PGT-A — Preimplantation Genetic Testing

Screen your IVF embryos for chromosomal abnormalities before transfer. Select only chromosomally normal embryos to maximise your chance of a successful, healthy pregnancy.

Benefits of PGT-A

📈

Higher IVF Success Rate

Transferring a chromosomally normal embryo significantly increases the chance of a successful pregnancy per transfer.

💔

Lower Miscarriage Risk

Most early miscarriages are caused by chromosomal abnormalities. PGT-A reduces this risk substantially.

🎯

Single Embryo Transfer

Confidence in the selected embryo enables single embryo transfer, reducing twin pregnancy risks.

⏱️

Fewer Failed Cycles

Fewer failed implantations and repeat IVF cycles, saving time, cost, and emotional burden.

Who Should Consider PGT-A?

  • ✓Advanced maternal age (35+)
  • ✓Recurrent miscarriage (2 or more losses)
  • ✓Repeated IVF failure (2+ failed transfers)
  • ✓Known chromosomal abnormality in either partner
  • ✓Previous pregnancy with chromosomal condition
  • ✓Severe male factor infertility

How PGT-A Works

1

Embryo Development

After egg retrieval and fertilisation via IVF or ICSI, embryos are cultured to the blastocyst stage (day 5–6).

2

Embryo Biopsy

3–5 cells are removed from the trophectoderm (the outer layer of the blastocyst that becomes the placenta) by a skilled embryologist.

3

Vitrification

All biopsied embryos are cryopreserved (frozen) while the biopsy samples are sent for analysis.

4

Genetic Analysis

The laboratory analyses all 23 pairs of chromosomes using NGS (Next Generation Sequencing). Results take 5–14 days.

5

Frozen Embryo Transfer

Only chromosomally normal (euploid) embryos are thawed and transferred in a subsequent cycle.

PGT-A — Frequently Asked Questions

What is PGT-A?▼
PGT-A (Preimplantation Genetic Testing for Aneuploidies) is a genetic screening test performed on embryos during an IVF cycle. A biopsy of a few cells is taken from each blastocyst-stage embryo and sent for chromosomal analysis. Only chromosomally normal (euploid) embryos are selected for transfer.
Who should consider PGT-A?▼
PGT-A is especially recommended for women over 35, couples with recurrent miscarriage, repeated IVF failure, a known chromosomal rearrangement in either partner, or a previous pregnancy affected by a chromosomal condition (e.g., Down syndrome).
Does PGT-A damage the embryo?▼
PGT-A involves a trophectoderm biopsy at the blastocyst stage (day 5–6), which removes a few cells from the part of the embryo that becomes the placenta — not the inner cell mass (which becomes the baby). Multiple studies confirm no significant impact on embryo viability or child health when performed by experienced embryologists.
What is the cost of PGT-A in India?▼
PGT-A adds approximately ₹50,000–₹1,20,000 to the cost of an IVF cycle, depending on the number of embryos biopsied and the genetic laboratory used. Discuss with your Iswarya fertility specialist whether PGT-A is appropriate for your situation.
Does PGT-A guarantee a successful pregnancy?▼
PGT-A significantly improves the probability of a successful pregnancy by ensuring the transferred embryo is chromosomally normal. However, it does not guarantee pregnancy — other factors such as uterine receptivity and implantation still play a role.

Ask About PGT-A for Your IVF Cycle

Our fertility specialists will help you decide if PGT-A is right for your situation.

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