Iswarya Fertility Centre & Women's Hospital
Gynecologist

Genetic Testing in IVF Success for Women Over 35

4 Sept 2025

Introduction

For women over 35, trying to conceive often comes with unique challenges. As age increases, the chances of chromosomal abnormalities in embryos become higher, which can lead to failed IVF cycles, miscarriages, or difficulty achieving a healthy pregnancy. This is where genetic testing of IVF embryos (PGT – Preimplantation Genetic Testing) plays a crucial role in improving success rates.

At Iswarya Fertility Centre, we use advanced genetic testing methods to help women over 35 conceive faster and with greater confidence.

What is Genetic Testing of Embryos in IVF?

Genetic testing, also known as Pre-implantation Genetic Testing (PGT), is performed on embryos created through IVF. Before transferring embryos into the uterus, a few cells are tested to check for chromosomal or genetic abnormalities. This process ensures that only healthy embryos are selected for implantation, which greatly increases the chances of a successful pregnancy.

Why is Genetic Testing Important for Women Over 35?

As women age, egg quality declines, leading to a higher risk of genetic conditions such as Down syndrome, miscarriage, or failed implantation. Genetic testing helps overcome these challenges by:

  • Selecting the healthiest embryos for transfer
  • Reducing the risk of miscarriage caused by chromosomal abnormalities
  • Increasing IVF success rates in women above 35
  • Shortening the time to pregnancy by avoiding failed IVF cycles
  • Reducing emotional and financial stress for couples trying to conceive

Why Age Affects Fertility

  • Women are born with a fixed number of eggs, and both egg quality and quantity decline with age.
  • After 35, the risk of producing embryos with chromosomal abnormalities increases significantly.
  • This can cause IVF cycle failures, higher chances of miscarriage, or genetic conditions in the baby.

What is Genetic Testing in IVF?

Genetic testing, also known as Preimplantation Genetic Testing (PGT), is a procedure where a few cells are taken from an IVF embryo and examined in a lab to check for chromosomal or genetic abnormalities.

Types of PGT include,

  • PGT-A (Aneuploidy screening): Checks if the embryo has the right number of chromosomes.
  • PGT-M (Monogenic disease testing): Screens for specific inherited genetic disorders.
  • PGT-SR (Structural rearrangements): Detects structural chromosome problems.

Benefits of Genetic Testing for Women Over 35

  • Higher IVF Success Rates – Healthy embryos have a better chance of implanting successfully.
  • Reduced Risk of Miscarriage – Minimizes the chances of pregnancy loss due to chromosomal errors.
  • Faster Time to Pregnancy – Selecting the healthiest embryo shortens the journey to conception.
  • Healthier Baby – Ensures the baby has the best chance of being born free from genetic disorders.
  • Fewer Failed IVF Cycles – Saves time, money, and emotional stress by reducing unsuccessful attempts.

Who Should Consider Genetic Testing?

  • Women aged 35 and above.
  • Couples with a history of repeated IVF failures.
  • Women who have experienced recurrent miscarriages.
  • Couples with known genetic disorders in the family.
  • Patients using donor eggs who want to maximize success.

The Process at Iswarya Fertility Centre

At Iswarya Fertility Centre, we follow a simple and safe process:

  • IVF Cycle – Eggs are retrieved and fertilized with sperm in the lab.
  • Embryo Development – Embryos grow for 5–6 days until the blastocyst stage.
  • Biopsy – A few cells are carefully taken from each embryo.
  • Genetic Analysis – Cells are tested for chromosomal or genetic issues.
  • Healthy Embryo Transfer – Only the best-quality, healthy embryos are transferred into the uterus.

Why Choose Iswarya Fertility Centre?

  • 35+ years of expertise in fertility care.
  • Advanced labs with the latest embryo testing technology.
  • Personalized treatment plans tailored for women over 35.
  • High success rates with IVF and PGT.
  • Compassionate care and support throughout your journey.

Conclusion

For women over 35, genetic testing of IVF embryos can make a life-changing difference. By identifying the healthiest embryos, it increases IVF success rates, reduces miscarriage risks, and helps couples achieve their dream of parenthood faster.At Iswarya Fertility Centre, we combine advanced genetic testing with world-class fertility care, making your journey to motherhood safer and more successful.

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