PGD & PGS – Genetic Testing for a Healthy Baby
8 Dec 2025
PGD & PGS – Genetic Testing for a Healthy Baby
Every couple dreams of having a healthy baby. Today, advanced reproductive technologies like PGD (Preimplantation Genetic Diagnosis) and PGS (Preimplantation Genetic Screening) make this possible by detecting genetic abnormalities before implanting the embryo during IVF.
These tests help reduce miscarriage risk, improve IVF success rates, and prevent the transmission of inherited disorders.
1. What Is PGD? (Preimplantation Genetic Diagnosis)
PGD is a specialized embryo test that checks for specific inherited genetic diseases.
When PGD is recommended:
If either parent carries a known genetic disorder
History of inherited diseases like Thalassemia, Sickle Cell Anaemia, Muscular Dystrophy, Cystic Fibrosis
Previous child affected with a genetic disorder
Couples with recurrent miscarriages due to genetic issues
PGD helps select embryos free from that particular disease, ensuring the baby does not inherit it.
2. What Is PGS / PGT-A? (Preimplantation Genetic Screening / Aneuploidy Testing)
PGS, also called PGT-A, screens embryos for chromosomal abnormalities such as missing or extra chromosomes.
PGS can detect issues like:
Down Syndrome
Turner Syndrome
Edward Syndrome
Chromosomal mismatch responsible for failed IVF cycles
PGS is especially useful for improving implantation and pregnancy success.
3. How PGD & PGS Are Done During IVF
Both PGD and PGS follow the same scientific process:
IVF procedure – eggs and sperm are fertilized in the lab
Embryo growth to Day 5 (blastocyst stage)
Embryo biopsy – a few cells are gently removed (safe for the baby)
Genetic testing in a specialized lab
Healthy embryos selected for transfer
This ensures only genetically normal embryos are implanted, leading to a healthier pregnancy.
4. Benefits of PGD & PGS
✔ Ensures a genetically healthy baby
Embryos with inherited diseases or chromosomal defects are identified early.
✔ Reduces miscarriage risk
Most miscarriages occur due to chromosomal abnormalities. PGS reduces this risk.
✔ Higher IVF success rates
Healthy embryos have better implantation potential.
✔ Reduces the risk of failed IVF cycles
Selecting normal embryos helps avoid repeated IVF failures.
✔ Peace of mind for high-risk couples
Especially those with a history of genetic conditions.
5. Who Should Consider PGD & PGS?
These tests are recommended for:
Women above 35 years
Men with high DNA fragmentation or severe sperm issues
Couples with previous IVF failures
Couples with a family history of genetic disease
Couples with recurrent pregnancy loss
Carriers of chromosomal translocations
If you fall into any of these categories, genetic testing can significantly improve outcomes.
6. Are PGD & PGS Safe?
Yes.
Embryo biopsy is a safe and advanced procedure that does not harm the embryo when performed by experienced embryologists.
Millions of healthy babies have been born worldwide following PGD/PGS testing.
7. Limitations to Know
No test can guarantee 100% accuracy
Some rare conditions may not be detectable
Not every embryo may be suitable for biopsy
Slightly increases the cost of IVF
However, the benefits often outweigh these limitations—especially for high-risk couples.
Why Choose Iswarya Fertility Centre for PGD & PGS in Chennai?
Iswarya Fertility Centre is one of India’s most trusted IVF hospitals offering advanced genetic testing technology.
What makes Iswarya the best choice:
✔ 37+ years of fertility expertise
✔ Advanced IVF laboratory with certified genetic testing partners
✔ Expert embryologists specializing in embryo biopsy
✔ Highly experienced fertility specialists –
Dr. Amutharani G, Dr. C Shanthi, Dr. Arun Muthuvel, Dr. Manipriya
✔ Over 1.5 lakh successful pregnancies
✔ 78.35% IVF success rate (among the highest in India)
✔ Specialized care for high-risk and advanced-age couples
✔ Transparent pricing + EMI support
At Iswarya, every step is taken to ensure couples achieve a safe, healthy pregnancy with confidence.
